Early analysis suggests that conolidine might not maximize tolerance in sufferers. Thereby providing a steady and successful therapy for pain without the have to have for expanding doses.Provided the mechanism of action of conolidine unlike opioids which in turn would do respiratory destruction. It wouldn't lead to a lethal overdose the way opioid

Exploration into conolidine has brought about discovery of an opioid receptor in your body named ACKR3/CXCR7. ACKR3 seems to be quite possibly the most desired focus on for conolidine, which also disregards the other 4 classical opioid receptors(three).This special system boosts the body’s natural pain relief program, offering helpful and Safe an